We are seeking a highly motivated Principal Scientist with a strong foundation in veterinary and/or biomedical sciences, including pathology, physiology, and toxicology, to join our Toxicology team. The successful candidate will assess preclinical safety of experimental compounds and will support drug development programs – from lead identification through clinical trial support – in a collaborative team environment, playing a pivotal role at all levels of preclinical development.
Oversee preclinical toxicology studies at external contract research organizations (CRO), including:
Facilitate study initiation by executing appropriate processes for contract implementation, test article procurement, protocol development, and timeline commitments.
Monitor studies for appropriate conduct, accuracy and timely completion; audit raw data for accuracy; and review draft reports for completion.
Anticipate study problems and opportunities and raise issues with suggested resolutions to supervisor.
Ensure appropriate project management and oversight with multiple CROs.
Evaluate individual and programmatic study data (anatomic pathology, clinical pathology, in-life parameters, etc.) as to the potential toxicity of experimental compounds in different animal species and prepare verbal and written summaries for internal discussions.
Work with the Toxicology team to develop optimal strategies to address specific safety issues and partner with project teams to select and advance Development compounds.
Serve as a key resource, providing scientific knowledge and expertise to cross-functional project teams.
Contribute to various regulatory documents and ensure compliance.
Build strong collaborative relationships with research and development teams to meet project, departmental, and company goals.
DVM/PhD or DVM; Board Certification in Veterinary Anatomic Pathology (ACVP) strongly preferred, or
PhD in Toxicology, Pathology, or related health science field; Board Certification in Toxicology (ABT) strongly preferred.
Solid foundation in animal and/or biomedical sciences, including pathology, physiology, and toxicology.
Excellent written and oral communication skills.
Strong commitment to quality and accountability.
Strong organizational and project management skills.
Effective problem solving skills and judgement.
Able to work in a strong collaborative environment.
Proficient knowledge of developmental and reproductive biology/toxicology.
Technical writing proficiency.
Level and compensation will be commensurate with experience.
Internal Number: TX601-NB
About Enanta Pharmaceuticals, Inc.
ABOUT ENANTA:Enanta Pharmaceuticals, Inc. is a publicly-traded (ENTA) research and development biotech focused on creating small molecule drugs for viral infections and liver diseases. We have already discovered novel protease inhibitors contained in some of the leading hepatitis C regimens now on the market and are currently focused on three disease targets: non-alcoholic steatohepatitis (NASH)/ primary biliary cholangitis (PBC), respiratory syncytial virus (RSV) and hepatitis B virus (HBV).Enanta is located in Watertown, MA, within the thriving innovation and cultural hub of Boston, just minutes from Harvard, MIT, and downtown Boston. Enanta has ample free parking and is also accessible via public transportation. Shopping and a variety of restaurants are within walking distance.